| Actin (Smooth Muscle) Antibody (IgG) | 15043X |
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| CPT Code(s): 83516 | Clinical Significance: Actin is the major antigen to which smooth muscle antibodies react in autoimmune hepatitis. F-Actin IgG antibodies are found in 52-85% of patients with autoimmune hepatitis (AIH) or chronic active hepatitis and in 22% of patients with primary bilary cirrhosis (PBC). Anti-actin antibodies have been reported in 3-18% of sera from normal healthy controls. |
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| Specimen Container: No additive serum separator tube |
| Preferred Specimen: 1 mL serum |
| Transport Temperaturer: Refrigerated |
| Methodology: Enzyme Linked Immunosorbent Immunoassay |
| Reference Range: Negative: <20 units Weak postitive: 20-30 units Positive: >30 |
| Reject Criteria: Microbially contaminated serum; Grossly hemolyzed specimens; Lipemic specimens; specimens containing heavy, visible particulate |
